Job Description
Are you ready to be a part of breakthrough research? Take action now by applying to this great opportunity!
Cedars-Sinai offers scientists unparalleled access to ground breaking technologies, facilities, and resources for conducting research related to an impressive range of diseases and disorders, from cancer, cardiology, and digestive diseases, to genetics, genomics, neurosciences, and women's health.
Dr. Hanane Touil invites you to consider this Postdoctoral Scientist opportunity to join her dynamic team!
About the Team
The laboratory of Dr. Touil is part of the Department of Neurology and Biomedical Sciences at Cedars-Sinai in Los Angeles. Dr. Touil leads a translational neuro-immunology research program that integrates rigorous functional neuro-immune assays with ground breaking computational approaches to investigate disease mechanisms underlying neuro-immunological disorders.
Her research focuses on Multiple Sclerosis (MS), compartmentalized inflammation within the central nervous system, and the molecular and cellular signatures of immunosenescence in both healthy aging and Alzheimer’s disease. Using deeply characterized human bio-specimens and advanced analytical methodologies. The laboratory seeks to identify biomarkers associated with prognosis, treatment response, and disease progression in order to advance early diagnosis and precision medicine strategies aimed at halting disease progression.
About the Role
Working independently but in close collaboration and in consultation with Dr. Touil and other Research Scientist in the team, the Postdoctoral Scientist will perform routine and sophisticated laboratory procedures throughout this training period. The candidate will lead a neuro-immunology based project conducting immunologic, transcriptomics and computational based analyses. This role consists in investigating the impact of existing disease modifying therapies on peripheral blood and central nervous based immune signatures during disease progression combining innovative technologies including sc-RNA-seq, CITE-Seq with proteomics and spectral flow cytometry combined with advanced clinical outcomes. The incumbent may develop, adapt, and implement new research techniques and protocols. This position is not responsible for generating grant funds.
Primary Duties and Responsibilities:
- Designs and performs experiments.
- Maintains experimental records and documentation and analyzes the results with the Principal Investigator.
- Analyzes interpret, summarizes, and compiles data.
- Operates and maintains equipment and instruments.
- May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed.
Department-Specific Duties:
- May collaborate with a multidisciplinary research team, including neurologists, computational biologists, bioengineers, neuroscientists and neuroimaging scientists.
- Process and manage human bio-specimens (Blood, Serum, Plasma, CSF cells and fluid).
- Performs multi-omics (sc-RNA-Seq, Spectral Flow Cytometry and proteomics).
- Implement innovative technologies to validate multi-omic findings.
- Performs functional assays including antigen-presentation, phagocytosis, cytotoxicity and cell proliferation.
- Will screen eligible patients with Multiple Sclerosis, dementia and Alzheimer’s disease ensuring compliance with inclusion and exclusion criteria.
- Follows SOPs and safety laboratory standards.
- Support general laboratory and departmental research activities.
- Assist with junior staff supervision as needed.
Qualifications
Education, Experience, and Skills:
- Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization.
- Ability to work independently and in a collaborative team — and should have excellent organizational and interpersonal skills.
- Acquires technical and theoretical knowledge of research project and objectives during one to five (1-5) year postdoctoral appointment.
- Proficiency in cytometry-related software.
- Experience in human or mouse immunology.
- Experience with completing milestone-driven projects.
- Ability to learn new protocols and platforms.
- Ability to employ computational tools to analyze multi-omics findings.
- Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
- Knowledge of safety standards and maintenance of specialized equipment.
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Our compensation philosophy
We offer competitive total compensation that includes pay, benefits, and other recognition programs for our employees. The base pay range shown above takes into account the wide range of factors that are considered in making compensation decisions including knowledge/skills; relevant experience and training; education/certifications/licensure; and other business and organizational factors. This base pay range does not include our comprehensive benefits package and any incentive payments that may be applicable to this role. Pay Transparency Non Discrimination Provision (PDF) (opens in new window)
Diversity and Inclusion at Cedars-Sinai
We are caretakers and innovators committed to the pursuit of equitable healthcare. But health equity is not possible without representation. Our commitment to diversity goes beyond demographics or checking boxes. Our people must reflect the diverse identities, experiences and geographies of the communities and patients we serve – because that’s what our patients, colleagues and communities deserve. Quality Care and Research—For All, By All (opens in new window).
Cedars-Sinai is an Equal Employment Opportunity employer.
Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at Applicant_Accommodation@cshs.org and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.
Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.
At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy. Cedars-Sinai’s AA Policy Statement (PDF) (opens in new window)